The Red Cross' first aid plane will fly into cyclone devastated Myanmar today as pressure builds on the reclusive Asian nation to open its borders to international aid.
The official death toll from the aftermath of the weekend's Cyclone Nagris stands at 22,980, but some experts fear that number could rise to 100,000.
Western countries, which have imposed tough sanctions against Burma over its human rights record, have been urging its military junta to urgently open its borders to help.
United States Secretary of State Condoleezza Rice said overnight that millions of dollars in assistance was waiting to be delivered and international disaster experts were on standby in nearby countries, ready to help, but they Burma is yet to give them visas.
"This is the kind of crisis which will only get worse without humanitarian assistance being made available from the international community," she said.
Some aid agencies with an established relationship with the Burmese government, such as the Red Cross and CARE Australia, have been able to begin work in the country.
Red Cross and Red Crescent, John Sparrow, said the organisation's first aid plane loaded with supplies would be flying from Malaysia into Burma today, and hoped it would be the first of many.
"We can't move quickly enough. We are a very happy though that later today our time we can get our first plane into Myanmar and we'll be taking shelter materials from Kuala Lumpur," Mr Sparrow told the Australian Nine Network this morning.
"So there are some positives. Of course we need to move much faster, there is no doubt about that. I'm looking right now at the positives."
But Mr Sparrow would not comment on the military regime's refusal to allow the freer flow of foreign aid.
"I think also it is time to be saying, for us right now, thank you for the go ahead on that first flight that's coming up today," Mr Sparrow said.
"For us it's a test run - for procedures, for getting a more active logistics pipeline going.
"We want to build on that. That's where we should be putting the emphasis right now."
CARE Australia spokesman Robert Yallop said it was not unusual for there to be a delay in aid getting into areas affected by major disasters, including New Orleans after Hurricane Katrina.
"In any disaster of this magnitude, no matter which government you are dealing with, it takes time to figure out the scale and the scope and the proportion," he told the Nine Network.
He said the challenge in Myanmar was enormous.
"It takes some time for the administrative arrangements, for the support and so on to be put in place," he told the Nine Network.
"CARE is making arrangements with the United Nations and the government authorities to bring in relief supplies within the next couple of days.
"But the real concern that we all have is to focus on how we get support and assistance to those in need."
He said he believed a UN relief flight from Italy was on its way to Rangoon.
"I have full confidence that the United Nations, working with the government authorities, will make the appropriate arrangements to get staff and to get materials and everything else in that is required for this relief effort.
He said relief was getting through to victims.
"Today we will be providing food and water to 10,000 people. In the coming days we will be providing assistance to another 50,000 people down in the delta
"That was given full support by the ministry of social welfare yesterday when our country director met with them.
"It is frustrating ... but I have complete optimism that it will happen and will happen in a way that is appropriate to the situation."